Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889351 | 0.82 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL9396171 | 0.81 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL283843 | 0.79 | ZDHHC20 (0.36) | ZDHHC20ZDHHC2 | |
| SCHEMBL23421037 | 0.78 | ZDHHC20 (0.54) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL19610469 | 0.78 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL15655347 | 0.77 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHR | |
| SCHEMBL4316811 | 0.77 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2 | |
| SCHEMBL4577787 | 0.76 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2TSHRMAPK1 | |
| SCHEMBL23421122 | 0.76 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL36287 | 0.76 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRMAPK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2008-02-14 | — | — | US | disclosed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070089246-A1 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | KRT18, CUTA, FLNA | ZDHHC20 1208/4885ZDHHC2 1900/4885TSHR 3393/4885 |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | ZDHHC20 2110/4885ZDHHC2 1978/4885TSHR 4753/4885 |
| US-20070089246-A1 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | KRT18, TYR, MICA | ZDHHC20 3815/4885ZDHHC2 4135/4885TSHR 1255/4885 |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | KRT18, VIM, DSG1 | ZDHHC20 2489/4885ZDHHC2 2739/4885TSHR 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.