SCHEMBL8765207

SCHEMBL8765207

C=CC(=O)N(CCCC(C)C)CCCC(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
TSHR P16473 2/20 0.35
KDM4C Q9H3R0 2/20 0.35
KDM4A O75164 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
BLM P54132 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
KMT2A Q03164 1/20 0.34
CA1 P00915 3/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
USP2 O75604 1/20 0.31
KDM1A O60341 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765499 0.94 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRKDM4CKDM4A
SCHEMBL9362963 0.92 ZDHHC20 (0.49) ZDHHC20ZDHHC2TSHRKDM4CKDM4A
SCHEMBL14528303 0.79 ZDHHC20 (0.34) ZDHHC20ZDHHC2TSHRCA1CA12
SCHEMBL372826 0.79 CA12 (0.48) ZDHHC20ZDHHC2TSHRMEN1KMT2A
SCHEMBL22420161 0.78 ZDHHC20 (0.39) ZDHHC20ZDHHC2TSHRCA1CA12
SCHEMBL26637804 0.78 ZDHHC20 (0.38) ZDHHC20ZDHHC2TSHR
SCHEMBL19801200 0.77 ALDH1A1 (0.38) ZDHHC20ZDHHC2TSHRMEN1KMT2A
SCHEMBL345353 0.77 ZDHHC20 (0.61) ZDHHC20ZDHHC2TSHRMEN1KMT2A
SCHEMBL5155628 0.76 KDM4C (0.42) ZDHHC20ZDHHC2KDM4CKDM4APHF8
SCHEMBL23421037 0.75 ZDHHC20 (0.54) ZDHHC20ZDHHC2TSHRCA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed