SCHEMBL10107013

SCHEMBL10107013

N#CCCSSCCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
LMNA P02545 5/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
APEX1 P27695 1/20 0.38
CYP1A2 P05177 2/20 0.37
FOLH1 Q04609 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.33
CYP2C19 P33261 3/20 0.32
CYP2D6 P10635 2/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11262277 0.84 LMNA (0.64) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL97811 0.82 MCL1 (0.41) TSHRLMNAKMT2ACYP1A2MEN1
Water SCHEMBL11221867 0.82 TSHR (0.93) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL97778 0.79 ALDH1A1 (0.50) TSHRHSD17B10TDP1ALDH1A1MAPT
SCHEMBL95982 0.79 TSHR (1.00) TSHRLMNAKMT2AHSD17B10TDP1
SCHEMBL2274837 0.78 TSHR (0.65) TSHRLMNAKMT2AHSD17B10TDP1
Water SCHEMBL18694993 0.76
SCHEMBL325311 0.76
Ammonia Solution, Strong SCHEMBL8958644 0.76 TSHR (0.93) TSHRLMNAKMT2AHSD17B10TDP1
Hydrochloric Acid SCHEMBL10457214 0.76 TSHR (0.93) TSHRLMNAKMT2AHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8637277-B2 Method for producing 3-mercaptopropionic acid or salt thereof MITSUI CHEMICALS, INC. (JP) 2014-01-28 US disclosed
US-8637277-B2 Method for producing 3-mercaptopropionic acid or salt thereof MITSUI CHEMICALS, INC. (JP) 2014-01-28 US disclosed
US-20120040418-A1 METHOD FOR PRODUCING 3-MERCAPTOPROPIONIC ACID OR SALT THEREOF MITSUI CHEMICALS INC. (JP) 2012-02-16 US disclosed
US-20120040418-A1 METHOD FOR PRODUCING 3-MERCAPTOPROPIONIC ACID OR SALT THEREOF MITSUI CHEMICALS INC. (JP) 2012-02-16 US disclosed