SCHEMBL10107293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16433641	0.77	ALDH1A1 (0.35)	BACE1LMNABACE2CYP11B2ALDH1A1
	SCHEMBL9231710	0.77	HDAC3 (0.41)	TDP2HDAC3HDAC1HDAC2HDAC6
	SCHEMBL4482310	0.71	HCAR2 (0.38)	BACE1BACE2ALDH1A1TSHR
	SCHEMBL13864262	0.69	HTR2A (0.35)	TDP2HDAC3HDAC1HDAC2HDAC6
	SCHEMBL2601632	0.68	BACE1 (0.42)	TDP2BACE1LMNAALDH1A1MEN1
	SCHEMBL20326725	0.67	PDE2A (0.42)	TDP2HDAC6PDE2AIDO1CYP11B2
	SCHEMBL5077850	0.67	HDAC3 (0.39)	TDP2HDAC3HDAC1HDAC2HDAC6
	SCHEMBL3213790	0.67	ALDH1A1 (0.32)	ALDH1A1MEN1KMT2A
	SCHEMBL5078505	0.67	HDAC3 (0.41)	TDP2HDAC3HDAC1HDAC2HDAC6
	SCHEMBL3218139	0.67	ALDH1A1 (0.32)	LMNAALDH1A1MEN1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.