Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498398 | 0.79 | MAPT (0.35) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL12069439 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1HSD17B10LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10107293 | 0.77 | TDP2 (0.40) | ALDH1A1LMNABACE1BACE2KMT2A | |
| SCHEMBL6290584 | 0.77 | KMT2A (0.38) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL4482310 | 0.75 | HCAR2 (0.38) | ALDH1A1SMN1; SMN2BACE1BACE2 | |
| SCHEMBL2601632 | 0.72 | BACE1 (0.42) | ALDH1A1LMNASMN1; SMN2BACE1KMT2A | |
| SCHEMBL19507134 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1HSD17B10LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6293971 | 0.70 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL5880790 | 0.69 | KDM1A (0.35) | ALDH1A1LMNASMN1; SMN2BACE1KMT2A | |
| SCHEMBL5635402 | 0.69 | KMT2A (0.41) | LMNAMAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45364-E1 | Cyclic amine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |