Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | PKLR | P30613 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387449 | 0.85 | S1PR2 (0.43) | S1PR2CCR1DRD2DRD4DRD3 | |
| SCHEMBL14077927 | 0.83 | DRD2 (0.36) | DRD2DRD4DRD3OPRM1OPRK1 | |
| SCHEMBL1010791 | 0.83 | GPR119 (0.43) | S1PR2DRD2OPRK1OPRD1 | |
| SCHEMBL5378448 | 0.82 | S1PR2 (0.39) | S1PR2CCR1MC4RDRD2DRD4 | |
| SCHEMBL23365187 | 0.80 | S1PR2 (0.40) | S1PR2CCR1DRD2DRD4DRD3 | |
| SCHEMBL5189318 | 0.80 | DRD2 (0.40) | DRD2DRD4DRD3OPRL1 | |
| SCHEMBL5376329 | 0.80 | ALDH1A1 (0.46) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL3384895 | 0.79 | DRD2 (0.47) | S1PR2MC4RDRD2DRD4DRD3 | |
| SCHEMBL2535627 | 0.77 | S1PR2 (0.39) | S1PR2CCR1DRD2DRD4DRD3 | |
| SCHEMBL5367535 | 0.77 | S1PR2 (0.57) | S1PR2DRD2OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948606-B1 | 3, 5-DISUBSTITUTED PHENYL-PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB AF NEUROSEARCH SWEDEN AB (DK) | 2011-01-05 | — | — | EP | disclosed |