Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330520 | 1.00 | CASP3 (0.44) | CASP3ALDH1A1NPSR1KMT2AHPGD | |
| SCHEMBL10107970 | 0.88 | ALDH1A1 (0.42) | ALDH1A1NPSR1KMT2AHPGDDRD3 | |
| SCHEMBL10198316 | 0.88 | ALDH1A1 (0.42) | ALDH1A1NPSR1KMT2AHPGDDRD3 | |
| SCHEMBL10150749 | 0.81 | HDAC7 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL9611861 | 0.80 | CASP3 (0.40) | CASP3ALDH1A1NPSR1KMT2AHPGD | |
| SCHEMBL12807351 | 0.80 | CASP3 (0.40) | CASP3ALDH1A1NPSR1KMT2AHPGD | |
| SCHEMBL10198307 | 0.80 | CASP3 (0.40) | CASP3ALDH1A1NPSR1KMT2AHPGD | |
| SCHEMBL7558328 | 0.79 | PLA2G2A (0.44) | KMT2A | |
| SCHEMBL102703 | 0.79 | PLA2G2A (0.44) | KMT2A | |
| SCHEMBL9287794 | 0.79 | KMT2A (0.43) | CASP3ALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044502-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2011044498-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2011044498-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011044502-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |