Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885364 | 0.76 | OR51E2 (0.35) | GRIK1GRIK2 | |
| SCHEMBL6635066 | 0.69 | GPR84 (0.53) | — | |
| SCHEMBL9064637 | 0.69 | GRIK1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL20075193 | 0.67 | GABRR1 (0.35) | GABRR1GABBR2GABBR1 | |
| SCHEMBL13716437 | 0.65 | — | — | |
| SCHEMBL27842827 | 0.65 | GPR84 (0.43) | — | |
| SCHEMBL28370901 | 0.64 | — | — | |
| SCHEMBL7155482 | 0.64 | GRIK1 (0.37) | GRIK1 | |
| SCHEMBL30387211 | 0.62 | — | — | |
| SCHEMBL8838837 | 0.62 | ALDH1A1 (0.31) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044502-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2011044502-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |