Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DPYD | Q12882 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102686 | 0.71 | TAAR1 (0.60) | TAAR1IP6K1IP6K3IP6K2KDM4E | |
| (Z)-1,2-Diphenylethene SCHEMBL10948488 | 0.65 | TAAR1 (0.53) | TAAR1IP6K1IP6K3IP6K2KDM4E | |
| (Z)-1,2-Diphenylethene SCHEMBL10948499 | 0.65 | TAAR1 (0.53) | TAAR1IP6K1IP6K3IP6K2KDM4E | |
| SCHEMBL13264504 | 0.64 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1CYP1A2LMNA | |
| SCHEMBL28198316 | 0.64 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1CYP1A2LMNA | |
| (Z)-1,2-Diphenylethene SCHEMBL443 | 0.63 | MAOB (0.73) | MEN1KMT2AALDH1A1LMNACYP11B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL9134296 | 0.63 | MAOB (0.73) | MEN1KMT2AALDH1A1LMNACYP11B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL9134305 | 0.63 | MAOB (0.73) | MEN1KMT2AALDH1A1LMNACYP11B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL22712863 | 0.63 | MAOB (0.73) | MEN1KMT2AALDH1A1LMNACYP11B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL21847984 | 0.63 | MAOB (0.73) | MEN1KMT2AALDH1A1LMNACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077811-A1 | PRODRUG FORMS OF KINASE INHIBITORS AND THEIR USE IN THERAPY | NTRK3, TK1, TNNI3K | TAAR1 174/4885IP6K1 1320/4885IP6K3 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.