SCHEMBL10108534

SCHEMBL10108534

c1ccc(-c2ccc(N(c3ccc(-c4cccc5c4sc4ccccc45)cc3)c3ccc(-c4cccc5c4sc4c5ccc5c4c4ccccc4n5-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PRKDC P78527 1/20 0.33
LIMK1 P53667 1/20 0.31
PARP14 Q460N5 1/20 0.31
F9 P00740 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10108543 0.98 ALOX5 (0.40) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL31791 0.95 ALOX5 (0.40) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL10108514 0.95 L3MBTL1 (0.37) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL10108480 0.94 ALOX5 (0.36) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL10108647 0.93 ALOX5 (0.41) ALOX5HSD17B10PRKDCPARP14F9
SCHEMBL10108520 0.92 ALOX5 (0.38) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL16283070 0.92 ALOX5 (0.43) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL16283051 0.91 ALOX5 (0.44) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL19129704 0.91 HSD17B10 (0.36) ALOX5HSD17B10KDM4EATML3MBTL1
SCHEMBL16283052 0.91 ALOX5 (0.44) ALOX5HSD17B10KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2940097-B1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME CHEIL IND INC (KR) 2019-03-20 EP disclosed
US-9246107-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-01-26 US disclosed
US-9246107-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-01-26 US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 US disclosed
EP-2450975-B1 Compound for organic optoelectronic device and organic light emitting diode including the same CHEIL IND INC (KR) 2014-01-08 EP disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 US disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE AOX1, OCIAD1, OCIAD2 ALOX5 380/4885HSD17B10 889/4885KDM4E 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.