SCHEMBL10108650

SCHEMBL10108650

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c6c7sc8ccccc8c7ccc6n(-c6ccccc6)c5c4)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.35
▸ TNKS O95271 1/20 0.33
▸ TNKS2 Q9H2K2 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ LIMK1 P53667 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14789556 0.99 HSD17B10 (0.34) HSD17B10TNKSTNKS2ALOX5KDM4E
SCHEMBL14789555 0.98 HSD17B10 (0.35) HSD17B10TNKSTNKS2ALOX5KDM4E
SCHEMBL19130046 0.97 TNKS (0.32) HSD17B10TNKSTNKS2ALOX5LIMK1
SCHEMBL14789637 0.96 HSD17B10 (0.32) HSD17B10TNKSTNKS2ALOX5
SCHEMBL14789480 0.96 TNKS (0.35) HSD17B10TNKSTNKS2ALOX5KDM4E
SCHEMBL14789574 0.95 HSD17B10 (0.32) HSD17B10TNKSTNKS2ALOX5LIMK1
SCHEMBL14789627 0.95 HSD17B10 (0.32) HSD17B10TNKSTNKS2ALOX5
SCHEMBL14789492 0.94 TNKS (0.34) HSD17B10TNKSTNKS2ALOX5KDM4E
SCHEMBL14789578 0.94 KDM4E (0.35) HSD17B10KDM4EATML3MBTL1
SCHEMBL14789573 0.94 HSD17B10 (0.32) HSD17B10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9246107-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-01-26 — — US disclosed
US-9246107-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display device including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2016-01-26 — — US disclosed
US-9178163-B2 Compound comprising a five-membered hetero ring, an organic electrical element using same and a terminal thereof DUK SAN NEOLUX CO., LTD. (KR) 2015-11-03 — — US disclosed
US-9178163-B2 Compound comprising a five-membered hetero ring, an organic electrical element using same and a terminal thereof DUK SAN NEOLUX CO., LTD. (KR) 2015-11-03 — — US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 — — US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 — — US disclosed
US-20150221873-A1 COMPOUND COMPRISING A FIVE-MEMBERED HETERO RING, AN ORGANIC ELECTRICAL ELEMENT USING SAME AND A TERMINAL THEREOF DUK SAN NEOLUX CO LTD (KR) 2015-08-06 — — US disclosed
US-20150221873-A1 COMPOUND COMPRISING A FIVE-MEMBERED HETERO RING, AN ORGANIC ELECTRICAL ELEMENT USING SAME AND A TERMINAL THEREOF DUK SAN NEOLUX CO LTD (KR) 2015-08-06 — — US disclosed
US-9005779-B2 Compound comprising a five-membered hetero ring, an organic electrical element using the same and a terminal thereof DUK SAN NEOLUX CO., LTD. (KR) 2015-04-14 — — US disclosed
US-9005779-B2 Compound comprising a five-membered hetero ring, an organic electrical element using the same and a terminal thereof DUK SAN NEOLUX CO., LTD. (KR) 2015-04-14 — — US disclosed
EP-2450975-B1 Compound for organic optoelectronic device and organic light emitting diode including the same CHEIL IND INC (KR) 2014-01-08 — — EP disclosed
US-20130069049-A1 COMPOUND COMPRISING A FIVE-MEMBERED HETERO RING, AN ORGANIC ELECTRICAL ELEMENT USING THE SAME AND A TERMINAL THEREOF DUKSAN HIGH METAL CO., LTD. (KR) 2013-03-21 — — US disclosed
US-20130069049-A1 COMPOUND COMPRISING A FIVE-MEMBERED HETERO RING, AN ORGANIC ELECTRICAL ELEMENT USING THE SAME AND A TERMINAL THEREOF DUKSAN HIGH METAL CO., LTD. (KR) 2013-03-21 — — US disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 — — US disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 — — US disclosed
EP-2450975-A2 Compound for organic optoelectronic device and organic light emitting diode including the same Cheil Industries Inc. (KR) 2012-05-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE AOX1, OCIAD1, OCIAD2 HSD17B10 889/4885TNKS 4775/4885TNKS2 4755/4885
US-20130069049-A1 COMPOUND COMPRISING A FIVE-MEMBERED HETERO RING, AN ORGANIC ELECTRICAL ELEMENT USING THE SAME AND A TERMINAL THEREOF VDAC2, OR10J3, VDAC1 HSD17B10 3361/4885TNKS 3511/4885TNKS2 3237/4885
US-20150221873-A1 COMPOUND COMPRISING A FIVE-MEMBERED HETERO RING, AN ORGANIC ELECTRICAL ELEMENT USING SAME AND A TERMINAL THEREOF EML4, KCNN4, OR10J3 HSD17B10 3675/4885TNKS 3118/4885TNKS2 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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