Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372326 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL5898951 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL1011863 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL11181373 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL152343 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL30417411 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL153538 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL155172 | 0.93 | — | — | |
| SCHEMBL30174149 | 0.93 | — | — | |
| Bromide SCHEMBL31070248 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372844-B1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INST OF TECHN (US) | 2011-01-05 | — | — | EP | claimed |
| US-6838489-B2 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | CYMETECH, LLC (US) | 2005-01-04 | — | — | US | claimed |
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | STERLING JA, L.C. | 2003-07-31 | — | — | US | claimed |
| EP-1423195-B1 | HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2016-03-02 | — | — | EP | disclosed |
| US-20120241250-A1 | Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers | EAKIN GEORGE R (US) | 2012-09-27 | — | — | US | disclosed |
| EP-1372844-B1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INST OF TECHN (US) | 2011-01-05 | — | — | EP | disclosed |
| CN-1911942-B | Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts | CALIFORNIA INST OF TECHN | 2010-06-23 | — | — | CN | disclosed |
| CN-1911942-A | Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts | CALIFORNIA INST OF TECHN (US) | 2007-02-14 | — | — | CN | disclosed |
| US-6936672-B2 | Mold addition polymerization of norbornene-type monomers using group 10 metal complexes | SUMITOMO BAKELITE CO., LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1423195-A4 | HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2005-06-29 | — | — | EP | disclosed |
| CN-1208360-C | In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes | SUMITOMO BAKELITE CO (JP) | 2005-06-29 | — | — | CN | disclosed |
| US-20030069374-A1 | Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY AND CYMETECH, LLP | 2003-04-10 | — | — | US | disclosed |
| US-6538087-B2 | (hetero)polycyclic polymer | PROMERUS, LLC | 2003-03-25 | — | — | US | disclosed |
| WO-2003011455-A1 | HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-02-13 | — | — | WO | disclosed |
| US-20020103317-A1 | Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same | SUMITOMO BAKELITE CO., LTD. (JP) | 2002-08-01 | — | — | US | disclosed |
| US-20020064896-A1 | Optical waveguides and methods for making the same | 3M INNOVATIVE PROPERTIES COMPANY | 2002-05-30 | — | — | US | disclosed |
| US-6350832-B1 | CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION | THE B. F. GOODRICH COMPANY | 2002-02-26 | — | — | US | disclosed |
| WO-2002010810-A2 | OPTICAL WAVEGUIDES AND METHODS FOR MAKING THE SAME | GOODRICH CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002010231-A2 | POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME | GOODRICH CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
| CN-1333788-A | In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes | GOODRICH CO B F (US) | 2002-01-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069374-A1 | Hexacoordinated ruthenium or osmium metal carbene metathesis catalysts | CLIC1, CBR1, KAT5 | POLA1 2549/4885 |
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | NQO1, NIT2, ALOX5 | POLA1 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.