Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20601589 | 0.85 | SLC18A3 (0.41) | SLC18A3SIGMAR1TSHRMAOAMAOB | |
| SCHEMBL12785527 | 0.78 | SLC6A2 (0.41) | TSHRMAOAMAOBMEN1KMT2A | |
| SCHEMBL15481959 | 0.76 | ALDH1A1 (0.35) | SLC18A3SIGMAR1TSHR | |
| SCHEMBL13221168 | 0.75 | BRD4 (0.36) | SLC18A3SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13971287 | 0.75 | BRD4 (0.36) | SLC18A3SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10772741 | 0.75 | BRD4 (0.36) | MAOAMAOBKDM1AMEN1KMT2A | |
| SCHEMBL11495069 | 0.74 | TSHR (0.36) | TSHRMAOAMAOBKDM1AMEN1 | |
| SCHEMBL10773600 | 0.72 | DRD2 (0.38) | MAOAMAOBKDM1AMEN1CYP2C19 | |
| SCHEMBL21880433 | 0.71 | AKR1C3 (0.42) | MEN1KMT2A | |
| SCHEMBL9599896 | 0.71 | SLC18A3 (0.36) | SLC18A3SIGMAR1TSHRKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120074395-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2012-03-29 | — | — | US | disclosed |
| US-20120074395-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2012-03-29 | — | — | US | disclosed |
| US-4710320-A | REACTING 1-AMINO-2-HALOGENO-4-HYDROXYANTHRAQUINONES WITH PHENOLS IN A SULFOLANE SOLVENT WITH AN ACID BINDING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-01 | — | — | US | disclosed |