Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772741 | 0.81 | BRD4 (0.36) | KDM1ABRD4ALDH1A1DRD2 | |
| SCHEMBL20601589 | 0.79 | SLC18A3 (0.41) | SLC18A3SIGMAR1KDM1ATSHR | |
| SCHEMBL10773600 | 0.78 | DRD2 (0.38) | KDM1ABRD4ALDH1A1GAADRD2 | |
| SCHEMBL15481959 | 0.74 | ALDH1A1 (0.35) | SLC18A3SIGMAR1BRD4ALDH1A1GAA | |
| SCHEMBL10109189 | 0.71 | SLC18A3 (0.35) | SLC18A3SIGMAR1KDM1ATSHR | |
| SCHEMBL21880433 | 0.69 | AKR1C3 (0.42) | BRD4ALDH1A1AKR1C3AKR1C1 | |
| SCHEMBL21239420 | 0.69 | DDB1 (0.35) | — | |
| SCHEMBL18362348 | 0.68 | — | — | |
| SCHEMBL2231326 | 0.68 | — | — | |
| SCHEMBL12785527 | 0.68 | SLC6A2 (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5339264-A | — | — | None | — | — | JP | disclosed |
| JP-H05339264-A | PRODUCTION OF 1-@(3754/24)2,3-DIDEOXY-D-GLYCERO-PENTOFURANOSYL) THYMINE DERIVATIVE | NOGUCHI KENKYUSHO | 1993-12-21 | — | — | JP | disclosed |