SCHEMBL10110539

SCHEMBL10110539

CC1(C)c2cc(-c3ccc4c(c3)oc3ccccc34)ccc2-c2ccc(N(c3ccc(-c4ccc(-c5ccccc5)cc4)cc3)c3cc4ccccc4c4ccccc34)cc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33
HCRTR1 O43613 1/20 0.31
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916359 1.00 MMP12 (0.33) MMP12MMP13HCRTR1GPR84
SCHEMBL9916740 1.00 MMP12 (0.33) MMP12MMP13HCRTR1GPR84
SCHEMBL9916751 0.99 MMP12 (0.33) MMP12MMP13HCRTR1GPR84
SCHEMBL18926251 0.98 MMP12 (0.34) MMP12MMP13HCRTR1GPR84
SCHEMBL20102253 0.94 HCRTR1 (0.33) MMP12MMP13HCRTR1
SCHEMBL9916307 0.94 PLA2G2A (0.34) GPR84
SCHEMBL9916628 0.94 PLA2G2A (0.34) GPR84
SCHEMBL10110068 0.94 PLA2G2A (0.34) GPR84
SCHEMBL20102282 0.94 HCRTR1 (0.33) MMP12MMP13HCRTR1
SCHEMBL17126750 0.94 PLA2G2A (0.34) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 US disclosed
US-9087997-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-07-21 US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 US disclosed
US-8703304-B2 Aromatic amine derivative and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20140061630-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161119-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE TYR, TERF2, SAT1 MMP12 4810/4885MMP13 4764/4885HCRTR1 4175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.