Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31177907 | 1.00 | LPO (0.54) | LPOSIGMAR1CMA1KDM4EALDH1A1 | |
| Bromide SCHEMBL2194872 | 0.98 | LPO (0.52) | LPOSIGMAR1CMA1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2011319 | 0.98 | LPO (0.52) | LPOSIGMAR1CMA1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31177921 | 0.98 | LPO (0.52) | LPOSIGMAR1CMA1KDM4EALDH1A1 | |
| SCHEMBL10522098 | 0.87 | SIGMAR1 (0.61) | SIGMAR1HRH3TAAR1 | |
| SCHEMBL1009271 | 0.81 | SIGMAR1 (0.47) | SIGMAR1CMA1KDM4EALDH1A1MAPT | |
| Bromide SCHEMBL2196195 | 0.80 | SIGMAR1 (0.46) | SIGMAR1CMA1KDM4EALDH1A1MAPT | |
| SCHEMBL31177901 | 0.80 | POLB (0.45) | KDM4EALDH1A1MAPTTP53HRH3 | |
| SCHEMBL28299282 | 0.80 | POLB (0.45) | KDM4EALDH1A1MAPTTP53HRH3 | |
| SCHEMBL7179785 | 0.78 | DRD2 (0.43) | KDM4EMAPTLMNATAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268652-A2 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009118475-A2 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-01 | — | — | WO | disclosed |