SCHEMBL10111017

SCHEMBL10111017

Cc1cc(C(=O)O)c(C)cc1S

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.44
▸ HPGD P15428 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ GAA P10253 1/20 0.44
▸ GABRP O00591 1/20 0.42
▸ GABRD O14764 1/20 0.42
▸ GABRA1 P14867 1/20 0.42
▸ GABRB1 P18505 1/20 0.42
▸ GABRG2 P18507 1/20 0.42
▸ GABRB3 P28472 1/20 0.42
▸ GABRA5 P31644 1/20 0.42
▸ GABRA3 P34903 1/20 0.42
▸ GABRA2 P47869 1/20 0.42
▸ GABRB2 P47870 1/20 0.42
▸ GABRA4 P48169 1/20 0.42
▸ GABRE P78334 1/20 0.42
▸ GABRA6 Q16445 1/20 0.42
▸ GABRG1 Q8N1C3 1/20 0.42
▸ GABRG3 Q99928 1/20 0.42
▸ GABRQ Q9UN88 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5658773 0.91 GABRP (0.42) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL70135 0.85 KDM4E (0.54) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL29264878 0.84 KDM4E (0.45) KDM4EHPGDHSD17B10GAAGABRP
Hydrochloric Acid SCHEMBL4352648 0.83 KDM4E (0.52) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL29350418 0.80 KDM4E (0.50) KDM4EHPGDHSD17B10GAAGABRP
Ethylene SCHEMBL6034661 0.80 KDM4E (0.50) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL238021 0.80 KDM4E (0.50) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL2400964 0.80 KDM4E (0.50) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL28022990 0.79 KDM4E (0.45) KDM4EHPGDHSD17B10GAAGABRP
SCHEMBL69934 0.78 KDM4E (0.50) KDM4EHPGDHSD17B10GAAGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9889412-B2 Composite gas separation membrane, gas separation module, gas separation apparatus and gas separation method FUJIFILM CORPORATION (JP) 2018-02-13 — — US disclosed
US-9889412-B2 Composite gas separation membrane, gas separation module, gas separation apparatus and gas separation method FUJIFILM CORPORATION (JP) 2018-02-13 — — US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 — — US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 — — US disclosed
US-9536633-B2 Metallic composite and composition thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-03 — — US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 — — US disclosed
US-20160184779-A1 COMPOSITE GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS AND GAS SEPARATION METHOD FUJIFILM CORPORATION (JP) 2016-06-30 — — US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 — — US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 — — US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 — — US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF CDH1, EPCAM, CD4 KDM4E 3592/4885HPGD 4215/4885HSD17B10 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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