⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10103689 | 0.73 | — | — | |
| SCHEMBL29435071 | 0.73 | NOS2 (0.30) | — | |
| SCHEMBL8846354 | 0.70 | — | — | |
| SCHEMBL10057749 | 0.69 | NOS3 (0.32) | — | |
| SCHEMBL13621430 | 0.69 | NISCH (0.32) | — | |
| SCHEMBL13355549 | 0.69 | NOS3 (0.32) | — | |
| SCHEMBL13452964 | 0.69 | NOS3 (0.32) | — | |
| SCHEMBL16181673 | 0.69 | NOS2 (0.32) | — | |
| SCHEMBL13453320 | 0.69 | NISCH (0.32) | — | |
| SCHEMBL13452968 | 0.69 | NISCH (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017193041-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES (US) | 2017-11-09 | — | — | WO | disclosed |
| US-20170319695-A1 | COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | SAGE THERAPEUTICS INC (US) | 2017-11-09 | — | — | US | disclosed |
| WO-2017193063-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES (US) | 2017-11-09 | — | — | WO | disclosed |
| US-20170305960-A1 | NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. | 2017-10-26 | — | — | US | disclosed |
| US-9780310-B2 | Heterocyclic compound for organic electroluminescent device and its application | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |
| US-9780310-B2 | Heterocyclic compound for organic electroluminescent device and its application | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |
| CN-107162951-A | A kind of preparation method of the 9 oxime derivate of isatin 3 | 宁波大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-107141246-A | A kind of preparation method of Isatine derivatives | 宁波大学 | 2017-09-08 | — | — | CN | disclosed |
| US-20160056388-A1 | HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION | TOSOH CORPORATION (JP) | 2016-02-25 | — | — | US | disclosed |
| US-20160056388-A1 | HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION | TOSOH CORPORATION (JP) | 2016-02-25 | — | — | US | disclosed |
| US-9169434-B2 | Phosphorescent metal complex, process for production and light-emitting component | OSRAM AG (DE) | 2015-10-27 | — | — | US | disclosed |
| US-9012038-B2 | Phosphorescent metal complex compound, method for the preparation thereof and radiating component | OSRAM GMBH (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20130046096-A1 | Phosphorescent Metal Complex, Process for Production and Light-Emitting Component | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| US-20120165335-A1 | CDK INHIBITORS | CURIS, INC. | 2012-06-28 | — | — | US | disclosed |
| US-20110187265-A1 | PHOSPHORESCENT METAL COMPLEX COMPOUND, METHOD FOR THE PREPARATION THEREOF AND RADIATING COMPONENT | OSRAM OLED GMBH (DE) | 2011-08-04 | — | — | US | disclosed |