Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688602 | 0.92 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2GAAHTTLMNA | |
| SCHEMBL13313846 | 0.91 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2EPHX1GAAHTT | |
| SCHEMBL10637569 | 0.88 | HPGD (0.62) | ALDH1A1SMN1; SMN2EPHX1GAAHTT | |
| SCHEMBL9023375 | 0.87 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2GAAHTTLMNA | |
| SCHEMBL21597667 | 0.87 | MEN1 (0.57) | ALDH1A1SMN1; SMN2GAALMNAMAPT | |
| SCHEMBL6984178 | 0.86 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2GAAHTTHPGD | |
| Thiophanate SCHEMBL20842 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2EPHX1LMNAHPGD | |
| Thiophanate SCHEMBL29398343 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2EPHX1LMNAHPGD | |
| SCHEMBL23727485 | 0.85 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2GAAHTTLMNA | |
| SCHEMBL23727417 | 0.84 | EPHX1 (0.62) | ALDH1A1SMN1; SMN2EPHX1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230773-A1 | Dipropargyloxybenzene compounds and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-05 | — | — | EP | claimed |
| EP-0190036-A2 | Fungicidal pyridine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-08-06 | — | — | EP | claimed |
| EP-0063905-B1 | FUNGICIDAL N-PHENYLCARBAMATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-14 | — | — | EP | claimed |
| EP-0100615-A1 | Fungicidal anilides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-02-15 | — | — | EP | claimed |
| US-12617785-B2 | Pyrrolo[2,3-b]pyridine-3-carboxamide compositions and methods for ameliorating hearing loss | THE ROCKEFELLER UNIVERSITY (US) | 2026-05-05 | — | — | US | disclosed |
| EP-4100008-B1 | PYRROLO [2,3-B]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS | UNIV ROCKEFELLER (US) | 2025-04-02 | — | — | EP | disclosed |
| US-20240343726-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | THE ROCKEFELLER UNIVERSITY (US) | 2024-10-17 | — | — | US | disclosed |
| EP-4380562-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | The Rockefeller University (US) | 2024-06-12 | — | — | EP | disclosed |
| US-20230137893-A1 | PYRROLO[2,3-b]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS | THE ROCKEFELLER UNIVERSITY (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230137893-A1 | PYRROLO[2,3-b]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS | THE ROCKEFELLER UNIVERSITY (US) | 2023-05-04 | — | — | US | disclosed |
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |
| CN-1150800-A | Alpha-phenylbutenic acid methyl ester | BASF AG (DE) | 1997-05-28 | — | — | CN | disclosed |
| CN-1143359-A | Phenyl acetic acid derivatives, process and intermediate products for their production and agents containing them | BASF AG (DE) | 1997-02-19 | — | — | CN | disclosed |
| CN-1121510-A | Substituted phenoxymethylphenyl derivatives, their preparation and their use for controlling pests and fungi | BASF AG (DE) | 1996-05-01 | — | — | CN | disclosed |
| CN-1120333-A | Imino-substituted phenylacetamides, their preparation and fungicides containing them | BASF AG (DE) | 1996-04-10 | — | — | CN | disclosed |
| CN-1109873-A | Thioimidates, their preparation and their use | BASF AKTEINGESELLSCHAFT (DE) | 1995-10-11 | — | — | CN | disclosed |
| CN-1101040-A | Diaryl derivatives and their use as crop protection agents | BASF AG (DE) | 1995-04-05 | — | — | CN | disclosed |
| US-5232484-A | Aqueous acid solution; mineralization; absence of large concentrations of organic solvents, chloride and sulfate | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-4086360-A | Phenyl thiol carbanilide derivatives, method for the preparation thereof and use thereof as fungicide for agriculture | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343726-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | LATS1, LATS2, YAP1 | ALDH1A1 3828/4885SMN1; SMN2 2198/4885EPHX1 4364/4885 |
| US-12617785-B2 | Pyrrolo[2,3-b]pyridine-3-carboxamide compositions and methods for ameliorating hearing loss | YAP1, LATS2, LATS1 | ALDH1A1 2546/4885SMN1; SMN2 2879/4885EPHX1 4502/4885 |
| US-20230137893-A1 | PYRROLO[2,3-b]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS | LATS2, LATS1, YAP1 | ALDH1A1 3775/4885SMN1; SMN2 2796/4885EPHX1 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.