Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688602 | 0.91 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7066252 | 0.88 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL1011218 | 0.86 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL21597667 | 0.86 | MEN1 (0.57) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL9023375 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL10668920 | 0.84 | RAB9A (0.64) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL13313846 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL23727080 | 0.84 | EPHX1 (0.62) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL23727417 | 0.84 | EPHX1 (0.62) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8609963 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324998-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030923-A1 | NOVEL AMINOTRIAZOLONE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-04-18 | — | — | WO | disclosed |