SCHEMBL10112508

SCHEMBL10112508

C/C=C\CCCC(=O)NCC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.55
CNR1 P21554 6/20 0.50
ALDH1A1 P00352 3/20 0.49
MEN1 O00255 2/20 0.49
BLM P54132 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
POLB P06746 1/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
APEX1 P27695 1/20 0.49
RECQL P46063 1/20 0.49
PMP22 Q01453 1/20 0.49
GPR18 Q14330 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SLC6A5 Q9Y345 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1584861 1.00 FAAH (0.55) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL1041069 1.00 FAAH (0.55) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL15468144 0.92 FAAH (0.62) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL29508694 0.89 FAAH (0.48) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL12464505 0.86 CNR1 (0.65) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL29382683 0.82 FAAH (0.50) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL22618724 0.82 TRPV1 (0.51) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL19557781 0.81 CNR1 (0.73) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL31540133 0.80 FAAH (0.68) FAAHCNR1ALDH1A1MEN1BLM
SCHEMBL23352597 0.80 EPHX2 (0.65) CNR1MEN1KMT2AMAPTSLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
EP-3725798-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-10-21 EP disclosed
WO-2019114666-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2019-06-20 WO disclosed
US-8101658-B2 Nitric oxide donating prostamides NICOX S.A. (FR) 2012-01-24 US disclosed
WO-2011075481-A1 INTRACAMERAL DEVICES FOR SUSTAINED DELIVERY ALLERGAN, INC. (US) 2011-06-23 WO disclosed
WO-2009136281-A1 NITRIC OXIDE DONATING PROSTAMIDES NICOX S.A. (FR) 2009-11-12 WO disclosed
US-7253295-B2 Chloride channel opener SUCAMPO AG (CH) 2007-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA FAAH 3537/4885CNR1 2470/4885ALDH1A1 1175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.