Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584861 | 1.00 | FAAH (0.55) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL10112508 | 1.00 | FAAH (0.55) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL15468144 | 0.92 | FAAH (0.62) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL29508694 | 0.89 | FAAH (0.48) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL12464505 | 0.86 | CNR1 (0.65) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL29382683 | 0.82 | FAAH (0.50) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL22618724 | 0.82 | TRPV1 (0.51) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL19557781 | 0.81 | CNR1 (0.73) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL31540133 | 0.80 | FAAH (0.68) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL23352597 | 0.80 | EPHX2 (0.65) | CNR1MEN1KMT2AMAPTSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174261-B | Method for preparing nitric oxide donor type prostaglandin analogue | 尼科斯股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024092085-A1 | AQUEOUS PHARMACEUTICAL COMPOSITIONS OF PROSTAGLANDINS | FAMYGEN LIFE SCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| EP-4288413-A1 | PROCESS FOR THE PREPARATION OF A NITRIC OXIDE DONATING PROSTAGLANDIN ANALOGUE | Nicox S.A. (FR) | 2023-12-13 | — | — | EP | disclosed |
| CN-116829537-A | Process for preparing prostaglandin analogues supplied with nitric oxide | 尼科斯股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-111757868-B | Nitric oxide donating prostaglandin analogs | 尼科斯股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2022167070-A1 | PROCESS FOR THE PREPARATION OF A NITRIC OXIDE DONATING PROSTAGLANDIN ANALOGUE | NICOX S.A. (FR) | 2022-08-11 | — | — | WO | disclosed |
| CN-114174261-A | Method for preparing nitric oxide donor type prostaglandin analogue | 尼科斯股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-20200123322-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2020-04-23 | — | — | US | disclosed |
| EP-2864308-A1 | COMPOUND AND METHOD | University Of Bristol (GB) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013186550-A1 | COMPOUND AND METHOD | UNIVERSITY OF BRISTOL (GB) | 2013-12-19 | — | — | WO | disclosed |
| EP-2488508-A1 | PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS | Cayman Chemical Company, Incorporated (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046569-A1 | PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS | CAYMAN CHEMICAL COMPANY (US) | 2011-04-21 | — | — | WO | disclosed |
| EP-2274279-A1 | NITRIC OXIDE DONATING PROSTAMIDES | Nicox S.A. (FR) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123322-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | ADRB3, PTGER3, CHRNE | FAAH 821/4885CNR1 210/4885ALDH1A1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.