Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112508 | 0.89 | FAAH (0.55) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL1584861 | 0.89 | FAAH (0.55) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL1041069 | 0.89 | FAAH (0.55) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL15468144 | 0.81 | FAAH (0.62) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL12464505 | 0.79 | CNR1 (0.65) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL22618724 | 0.76 | TRPV1 (0.51) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL29382683 | 0.76 | FAAH (0.50) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL19557781 | 0.75 | CNR1 (0.73) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL2639337 | 0.74 | CNR1 (0.79) | FAAHCNR1ALDH1A1MEN1BLM | |
| SCHEMBL18240162 | 0.74 | CNR1 (0.79) | FAAHCNR1ALDH1A1MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174261-A | Method for preparing nitric oxide donor type prostaglandin analogue | 尼科斯股份有限公司 | 2022-03-11 | — | — | CN | disclosed |