SCHEMBL10112574

SCHEMBL10112574

c1ccc(-c2nnc(-c3ccccc3-c3c4ccccc4c(-c4ccccc4-c4nnc(-c5ccccc5)o4)c4c(N(c5ccccc5)c5ccc6c(c5)c5ccccc5n6-c5ccccc5)cccc34)o2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
RAB9A P51151 6/20 0.36
KDM4E B2RXH2 6/20 0.36
NPC1 O15118 5/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
HPGD P15428 5/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
PTGS2 P35354 2/20 0.32
TSHR P16473 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 4/20 0.31
LMNA P02545 3/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10112695 0.94 RAB9A (0.39) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10112566 0.90 NPC1 (0.34) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10112569 0.90 NPC1 (0.34) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10112570 0.89 RAB9A (0.40) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL14466541 0.89 RAB9A (0.41) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL8406172 0.88 KDM4E (0.38) KDM4EATML3MBTL1KMT2A
SCHEMBL14466537 0.88 RAB9A (0.42) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10112693 0.85 NPC1 (0.35) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10112694 0.85 RAB9A (0.41) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL10112437 0.85 RAB9A (0.41) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110980-B2 Anthracene derivative, and light emitting element, light emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-07 US disclosed
US-8110980-B2 Anthracene derivative, and light emitting element, light emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-07 US disclosed
EP-1918350-B1 Anthracene derivative, and light emitting element, light emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LAB (JP) 2010-08-11 EP disclosed
US-20100164376-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-07-01 US disclosed
US-20100164376-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-07-01 US disclosed
US-7674914-B2 novel anthracene derivative represented by General Formula (1) is provided, which enables the production of a light-emitting element with high luminous efficiency and a long lifetime. A high-performance light-emitting device and electronic device in which the anthracene derivative light emitting diode SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-09 US disclosed
US-7674914-B2 novel anthracene derivative represented by General Formula (1) is provided, which enables the production of a light-emitting element with high luminous efficiency and a long lifetime. A high-performance light-emitting device and electronic device in which the anthracene derivative light emitting diode SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-09 US disclosed
EP-1918350-A2 Anthracene derivative, and light emitting element, light emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-07 EP disclosed
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-05-01 US disclosed
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative AMY1A, CYP1A1, CRY1 ALDH1A1 16/4885RAB9A 2483/4885KDM4E 3476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.