SCHEMBL10112774

SCHEMBL10112774

Cc1ccc(C)c(C(=O)c2ccc(Oc3ccc(S(=O)(=O)O)cc3)c(S(=O)(=O)O)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
KMT2A Q03164 2/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.38
MRGPRX1 Q96LB2 1/20 0.38
MAPK1 P28482 1/20 0.38
TBXA2R P21731 6/20 0.38
CYP1A2 P05177 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13671429 0.87 MMP13 (0.43) SMN1; SMN2MAPTTP53ALDH1A1HPGD
SCHEMBL10112773 0.85 SNCA (0.39) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL10112772 0.84 ALDH1A1 (0.39) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL12665256 0.83 POLB (0.45) SMN1; SMN2MAPTALDH1A1KMT2AHTT
SCHEMBL10112765 0.81 MAPT (0.45) MAPTTP53ALDH1A1LMNAKMT2A
SCHEMBL14510710 0.80 MAPT (0.44) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL10112768 0.80 ALDH1A1 (0.40) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL17169234 0.79 ALDH1A1 (0.49) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL10112776 0.79 ALDH1A1 (0.40) SMN1; SMN2MAPTTP53ALDH1A1LMNA
SCHEMBL17207932 0.78 HTT (0.54) SMN1; SMN2MAPTTP53HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20160158692-A1 RESIN COMPOSITION AND CARBON DIOXIDE GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-09 US disclosed
US-20160158692-A1 RESIN COMPOSITION AND CARBON DIOXIDE GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-09 US disclosed
US-20140154610-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF JSR CORPORATION (JP) 2014-06-05 US disclosed
US-20140154610-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF JSR CORPORATION (JP) 2014-06-05 US disclosed
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed