Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12882346 | 0.85 | LMNA (0.61) | HDAC1HDAC2HDAC8HDAC3POLB | |
| SCHEMBL10113877 | 0.83 | HDAC1 (0.57) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL10113178 | 0.83 | ALDH1A1 (0.56) | POLBCA2CA1ALDH1A1MEN1 | |
| SCHEMBL10115242 | 0.83 | HDAC3 (0.60) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL10113494 | 0.83 | STS (0.50) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL17089976 | 0.81 | CA1 (0.50) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL10113591 | 0.79 | HDAC1 (0.53) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL10113605 | 0.79 | MGLL (0.44) | POLBCA2CA1ALDH1A1KMT2A | |
| SCHEMBL13716200 | 0.77 | HDAC1 (0.60) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL10113596 | 0.75 | TRPV1 (0.48) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
| US-20070015762-A1 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | NPY5R, NPY1R, NPY2R | HDAC1 1995/4885HDAC2 1548/4885HDAC10 1376/4885 |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | HDAC1 1703/4885HDAC2 1458/4885HDAC10 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.