SCHEMBL10114767

SCHEMBL10114767

CCn1c2ccc(C)cc2c2cc(C(C)c3cccc4ccccc34)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.41
KDM4E B2RXH2 5/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 2/20 0.41
HBB P68871 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RORC P51449 3/20 0.41
RORA P35398 2/20 0.41
RORB Q92753 2/20 0.41
PGR P06401 1/20 0.41
LMNA P02545 5/20 0.40
CNR2 P34972 2/20 0.39
POLB P06746 2/20 0.38
PTGER4 P35408 2/20 0.38
NPY5R Q15761 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14946148 0.82 CYP1A2 (0.35) ALDH1A1RORCRORARORBPGR
SCHEMBL10114737 0.82 MAPT (0.43) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL23175748 0.78 KDM4E (0.49) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL23175747 0.78 KDM4E (0.49) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL23175746 0.78 KDM4E (0.49) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL10114699 0.77 MEN1 (0.46) MEN1KMT2APOLB
SCHEMBL156150 0.75 MAPT (0.67) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL29643308 0.75 MAPT (0.67) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL19271261 0.74 MAPT (0.49) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL28624759 0.74 MAPT (0.48) MAPTKDM4EMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722841-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-13 US disclosed
US-8674052-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed