SCHEMBL14946148

SCHEMBL14946148

C#Cn1c2ccc(C)cc2c2cc(C(C)c3cccc4ccccc34)ccc21

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ADRA2A P08913 4/20 0.34
ADRA2B P18089 4/20 0.34
ADRA2C P18825 4/20 0.34
ADRA1A P35348 2/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1B P35368 1/20 0.34
CYP2A6 P11509 1/20 0.34
LTC4S Q16873 1/20 0.32
PHGDH O43175 1/20 0.31
TSHR P16473 1/20 0.31
PGR P06401 1/20 0.30
RORA P35398 1/20 0.30
RORC P51449 1/20 0.30
RORB Q92753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14946149 0.82 BCHE (0.35) ADRA2APGRRORARORCRORB
SCHEMBL10114767 0.82 MAPT (0.41) ALDH1A1PGRRORARORCRORB
SCHEMBL10114699 0.76 MEN1 (0.46) CYP1A2ADRA2AADRA2BADRA2CADRA1A
SCHEMBL16945418 0.71 LMNA (0.42) ALDH1A1ADRA2AADRA2BADRA2CADRA1A
SCHEMBL15960966 0.67 HPGD (0.46) CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A
SCHEMBL2992858 0.66 SLC6A4 (0.53) CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A
SCHEMBL28931321 0.66 SLC6A4 (0.53) CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A
SCHEMBL2998678 0.66 ALDH1A1 (0.60) CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A
SCHEMBL16303831 0.66 BCHE (0.50) ALDH1A1PHGDHTSHRPGRRORA
SCHEMBL20173213 0.65 KDM4E (0.46) CYP1A2ALDH1A1CYP2C9CYP2C19ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130122710-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-16 US disclosed