Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 8/20 | 0.50 |
| ▸ | CA2 | P00918 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113961 | 0.88 | NAMPT (0.49) | RXFP1NAMPTMEN1KMT2ANPSR1 | |
| SCHEMBL10113958 | 0.86 | NAMPT (0.66) | RXFP1KDM4ENAMPTMEN1KMT2A | |
| SCHEMBL13204270 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4ENAMPTMEN1KMT2A | |
| SCHEMBL10133540 | 0.86 | NAMPT (0.50) | RXFP1ALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL10114938 | 0.86 | PTPN1 (0.56) | NAMPTMEN1KMT2ANPSR1 | |
| SCHEMBL10114691 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4ENAMPTMEN1KMT2A | |
| SCHEMBL13204426 | 0.86 | PTPN1 (0.56) | NAMPTMEN1KMT2ANPSR1 | |
| SCHEMBL10114972 | 0.86 | POLB (0.56) | RXFP1ALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL14424384 | 0.86 | POLB (0.56) | RXFP1ALDH1A1NAMPTMEN1KMT2A | |
| SCHEMBL13204281 | 0.85 | L3MBTL1 (0.56) | NAMPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | RXFP1 53/4885ALDH1A1 4599/4885CA1 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.