Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204411 | 1.00 | LMNA (0.56) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL10114923 | 0.91 | LMNA (0.56) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL14424382 | 0.91 | LMNA (0.56) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL14424259 | 0.88 | LMNA (0.54) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL10114565 | 0.88 | LMNA (0.54) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL10114972 | 0.87 | POLB (0.56) | LMNAALDH1A1NPSR1KMT2APOLB | |
| SCHEMBL14424384 | 0.87 | POLB (0.56) | LMNAALDH1A1NPSR1KMT2APOLB | |
| SCHEMBL13204425 | 0.85 | LMNA (0.59) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL10114988 | 0.85 | LMNA (0.59) | LMNASMN1; SMN2GAAUSP2HPGD | |
| SCHEMBL13204423 | 0.84 | RHOA (0.54) | LMNASMN1; SMN2GAAUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | LMNA 2068/4885SMN1; SMN2 2197/4885GAA 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.