Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926414 | 0.90 | TDP1 (0.52) | TDP1L3MBTL1KMT2AGABRA2GABRB2 | |
| Ammonia Solution, Strong SCHEMBL27669870 | 0.89 | TDP1 (0.51) | TDP1L3MBTL1KMT2AGABRA2GABRB2 | |
| SCHEMBL21655284 | 0.88 | TDP1 (0.43) | TDP1L3MBTL1KMT2AGABRB3GABRA2 | |
| SCHEMBL30861677 | 0.86 | TDP1 (0.58) | TDP1L3MBTL1KMT2AGABRB3GABRA2 | |
| SCHEMBL9290492 | 0.86 | TDP1 (0.58) | TDP1L3MBTL1KMT2AGABRB3GABRA2 | |
| SCHEMBL30861680 | 0.86 | TDP1 (0.58) | TDP1L3MBTL1KMT2AGABRB3GABRA2 | |
| Ammonia Solution, Strong SCHEMBL20298816 | 0.84 | TDP1 (0.56) | TDP1L3MBTL1KMT2AGABRB3GABRA2 | |
| SCHEMBL19584403 | 0.84 | TDP1 (0.56) | TDP1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL1122017 | 0.83 | TDP1 (0.55) | TDP1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL16586047 | 0.83 | TDP1 (0.55) | TDP1L3MBTL1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900660-B1 | HERBICIDAL AND FUNGICIDAL 3-HETEROARYLISOXAZOLIN-5-CARBOXAMIDES AND 3-HETEROARYLISOXAZOLIN-5-THIOAMIDES | BAYER CROPSCIENCE AG (DE) | 2018-01-17 | — | — | EP | disclosed |
| EP-2900644-B1 | HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-THIOAMIDES | BAYER CROPSCIENCE AG (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-20120021074-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2012-01-26 | — | — | US | disclosed |
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | BAYER CROP SCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | BAYER CROP SCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2009049798-A1 | IMINOHETEROCYCLES FOR INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021074-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | P2RX3, P2RX1, P2RX2 | TDP1 1569/4885L3MBTL1 3218/4885KMT2A 4097/4885 |
| US-20110190365-A1 | Insecticidal 4-phenyl-1H-pyrazoles | CYP4X1, CYP4B1, CYP3A4 | TDP1 3826/4885L3MBTL1 1457/4885KMT2A 2623/4885 |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | TDP1 148/4885L3MBTL1 1150/4885KMT2A 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.