SCHEMBL1122017

SCHEMBL1122017

NCCc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 6/20 0.50
HTT P42858 2/20 0.48
RAB9A P51151 1/20 0.48
PLAU P00749 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAPT P10636 1/20 0.47
GLA P06280 1/20 0.46
GAA P10253 2/20 0.45
MEN1 O00255 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31255200 1.00 TDP1 (0.55) TDP1L3MBTL1KMT2AALDH1A1HTT
Hydrochloric Acid SCHEMBL1122045 0.98 TDP1 (0.54) TDP1L3MBTL1KMT2AALDH1A1HTT
Hydrochloric Acid SCHEMBL6603171 0.98 TDP1 (0.54) TDP1L3MBTL1KMT2AALDH1A1HTT
SCHEMBL3771280 0.90 TDP1 (0.52) TDP1L3MBTL1KMT2AALDH1A1HTT
Acetic Acid SCHEMBL4444086 0.90 KMT2A (0.53) TDP1L3MBTL1KMT2AALDH1A1HTT
SCHEMBL3926418 0.89 TDP1 (0.51) TDP1L3MBTL1KMT2AALDH1A1HTT
Hydrazine SCHEMBL3964002 0.87 TDP1 (0.50) TDP1L3MBTL1KMT2AALDH1A1HTT
SCHEMBL635541 0.86 TDP1 (0.58) TDP1L3MBTL1KMT2AALDH1A1HTT
SCHEMBL31255260 0.86 TDP1 (0.58) TDP1L3MBTL1KMT2AALDH1A1HTT
Hydrochloric Acid SCHEMBL637924 0.84 TDP1 (0.56) TDP1L3MBTL1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099838-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF FLUOPYRAM BEST AGROLIFE LIMITED (IN) 2026-05-15 WO claimed
CN-118772049-B Preparation process of 3-chloro-2-aminoethyl-5-trifluoromethyl pyridine 山东滨农科技有限公司 2025-04-11 CN claimed
CN-119684204-A Preparation method of fluopyram intermediate 顺毅南通化工有限公司 2025-03-25 CN claimed
CN-119462491-A Fluopicola strain method for synthesizing amide 南通泰禾化工股份有限公司 2025-02-18 CN claimed
CN-119219553-A Synthesis method of 3-chloro-2-aminoethyl-5-trifluoromethyl pyridine 江苏快达农化股份有限公司 2024-12-31 CN claimed
CN-118772049-A Preparation process of 3-chloro-2-aminoethyl-5-trifluoromethyl pyridine 山东滨农科技有限公司 2024-10-15 CN claimed
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN claimed
CN-112552231-B Synthetic method of 2- (3-chloro-5- (trifluoromethyl) pyridine-2-yl) ethylamine 南京正荣医药化学有限公司 2022-03-11 CN claimed
EP-3558944-B1 HYDROGENATION OF A SUBSTITUTED 2-METHYL CYANOPYRIDYL DERIVATIVE IN THE PRESENCE OF A RANEY COBALT CATALYST BAYER CROPSCIENCE AG (DE) 2022-03-09 EP claimed
CN-112552231-A Synthetic method of 2- (3-chloro-5- (trifluoromethyl) pyridine-2-yl) ethylamine 南京正荣医药化学有限公司 2021-03-26 CN claimed
US-20160280648-A1 CATALYTIC HYDROGENATION OF NITRILES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-09-29 US claimed
EP-3068766-A1 CATALYTIC HYDROGENATION OF NITRILES Bayer CropScience Aktiengesellschaft (DE) 2016-09-21 EP claimed
WO-2015071230-A1 CATALYTIC HYDROGENATION OF NITRILES BAYER CROPSCIENCE AG (DE) 2015-05-21 WO claimed
JP-4794570-B2 2011-10-19 JP claimed
EP-1833793-B1 PROCESS FOR THE PREPARATION OF A 2-ETHYLAMINOPYRIDINE DERIVATIVE BAYER CROPSCIENCE AG (DE) 2010-12-08 EP claimed
US-7777045-B2 Process for the preparation of a 2-ethylaminopyridine derivative BAYER CROPSCIENCE S.A. (FR) 2010-08-17 US claimed
US-20080114176-A1 Process For The Preparation Of A 2-Ethylaminopyridine Derivative BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2008-05-15 US claimed
EP-1833793-A1 PROCESS FOR THE PREPARATION OF A 2-ETHYLAMINOPYRIDINE DERIVATIVE Bayer CropScience S.A. (FR) 2007-09-19 EP claimed
WO-2006067106-A1 PROCESS FOR THE PREPARATION OF A 2-ETHYLAMINOPYRIDINE DERIVATIVE BAYER CROPSCIENCE SA (FR) 2006-06-29 WO claimed
EP-1674455-A1 Process for the preparation of a 2-ethylaminopyridine derivative Bayer CropScience S.A. (FR) 2006-06-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080114176-A1 Process For The Preparation Of A 2-Ethylaminopyridine Derivative SDHA, UROD, SDHB TDP1 2739/4885L3MBTL1 4875/4885KMT2A 1098/4885
US-20160280648-A1 CATALYTIC HYDROGENATION OF NITRILES PNMT, HNMT, PYCR1 TDP1 1031/4885L3MBTL1 4151/4885KMT2A 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.