Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610265 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 | |
| SCHEMBL14526476 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 | |
| SCHEMBL11034492 | 0.93 | RELA (0.52) | ALOX5PTGS1PTGS2RELAAPP | |
| SCHEMBL4402918 | 0.93 | RELA (0.52) | ALOX5PTGS1PTGS2RELAAPP | |
| SCHEMBL14295899 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 | |
| SCHEMBL16489724 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 | |
| SCHEMBL4403035 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 | |
| SCHEMBL12292312 | 0.93 | RELA (0.52) | ALOX5PTGS1PTGS2RELAAPP | |
| SCHEMBL14847302 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 | |
| SCHEMBL17122433 | 0.93 | ALOX5 (0.51) | ALOX5PTGS1PTGS2RELAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120321348-A1 | IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
| EP-2146251-B1 | Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge | RICOH CO LTD (JP) | 2012-02-08 | — | — | EP | disclosed |