SCHEMBL13610265

SCHEMBL13610265

CCc1ccc(N(c2ccc(C)cc2)c2ccc(/C=C/c3ccc(/C=C/c4ccc(N(c5ccc(C)cc5)c5ccc(CC)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.51
▸ PTGS1 P23219 2/20 0.51
▸ PTGS2 P35354 2/20 0.51
▸ MEN1 O00255 3/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ NFE2L2 Q16236 3/20 0.45
▸ APOBEC3A P31941 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ APOBEC3G Q9HC16 2/20 0.45
▸ TUBB1 Q9H4B7 1/20 0.45
▸ RELA Q04206 2/20 0.42
▸ GAA P10253 2/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ GFER P55789 1/20 0.41
▸ HCRTR2 O43614 1/20 0.41
▸ KDM4A O75164 3/20 0.40
▸ KDM2A Q9Y2K7 3/20 0.40
▸ CA1 P00915 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16489724 1.00 ALOX5 (0.51) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL17122433 1.00 ALOX5 (0.51) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL14847302 1.00 ALOX5 (0.51) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL14526476 1.00 ALOX5 (0.51) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL4403035 1.00 ALOX5 (0.51) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL14295899 1.00 ALOX5 (0.51) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL20343030 0.95 ALOX5 (0.47) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL10116784 0.93 TRPM8 (0.46) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL10039797 0.92 ALOX5 (0.53) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL13978794 0.92 ALOX5 (0.53) ALOX5PTGS1PTGS2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622232-B2 Electrophotographic photoreceptor and electrophotographic imaging apparatus employing the photoreceptor SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-11-24 — — US disclosed
US-7622232-B2 Electrophotographic photoreceptor and electrophotographic imaging apparatus employing the photoreceptor SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-11-24 — — US disclosed
EP-1821151-A1 Electrophotographic photoreceptor and electrophotographic imaging apparatus employing the photoreceptor Samsung Electronics Co., Ltd. (KR) 2007-08-22 — — EP disclosed
US-20070190439-A1 Electrophotographic photoreceptor and electrophotographic imaging apparatus employing the photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2007-08-16 — — US disclosed
US-20070190439-A1 Electrophotographic photoreceptor and electrophotographic imaging apparatus employing the photoreceptor SAMSUNG ELECTRONICS CO., LTD. 2007-08-16 — — US disclosed
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