Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18273960 | 0.89 | MAPT (0.68) | MAPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL6420228 | 0.82 | MAPT (0.72) | MAPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL1706332 | 0.79 | APP (0.61) | MAPTHSD17B10KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL4119472 | 0.76 | TRPV1 (0.63) | KDM4EALDH1A1HPGDPTGS1TRPV1 | |
| SCHEMBL10116816 | 0.75 | MAPT (0.70) | MAPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL6418730 | 0.74 | MTNR1A (0.66) | ALDH1A1LMNAGAATYRACHE | |
| SCHEMBL27160492 | 0.74 | GAA (0.60) | MAPTALDH1A1LMNATRPV1GAA | |
| SCHEMBL107219 | 0.73 | MAPT (0.71) | MAPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL175651 | 0.73 | APP (0.57) | MAPTHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL29116446 | 0.72 | APP (0.64) | MAPTHSD17B10KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916652-B2 | Multi-armed catechol compound blends | KENSEY NASH CORPORATION (US) | 2014-12-23 | — | — | US | disclosed |
| US-8119742-B2 | Multi-armed catechol compound blends | KNC NER ACQUISITION SUB, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | NERITES CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | COMT, HAAO, PNMT | MAPT 909/4885HSD17B10 859/4885KDM4E 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.