Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.61 |
| ▸ | YWHAG | P61981 | 1/20 | 0.50 |
| ▸ | IAPP | P10997 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrocaffeic Acid SCHEMBL7058919 | 0.84 | IAPP (0.65) | APPIAPPGAAKDM4ERGS12 | |
| Dihydrocaffeic Acid SCHEMBL29351390 | 0.84 | IAPP (0.65) | APPIAPPGAAKDM4ERGS12 | |
| Dihydrocaffeic Acid SCHEMBL245530 | 0.84 | IAPP (0.65) | APPIAPPGAAKDM4ERGS12 | |
| SCHEMBL175651 | 0.79 | APP (0.57) | APPYWHAGIAPPGAAKDM4E | |
| SCHEMBL15391990 | 0.79 | GAA (0.69) | APPYWHAGGAAKDM4ERGS12 | |
| SCHEMBL10117441 | 0.79 | MAPT (0.51) | APPGAAKDM4ELMNAMAPT | |
| SCHEMBL490726 | 0.78 | GAA (0.71) | GAALMNATSHRNFKB1APEX1 | |
| SCHEMBL31337638 | 0.78 | GAA (0.71) | GAALMNATSHRNFKB1APEX1 | |
| SCHEMBL29116446 | 0.78 | APP (0.64) | APPYWHAGIAPPGAAKDM4E | |
| Dihydrocaffeic Acid SCHEMBL31017610 | 0.78 | IAPP (0.57) | APPIAPPGAAKDM4ERGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | disclosed |
| EP-1113790-B1 | USE OF A CINNAMIC ACID DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR PREVENTING OR TREATING ELEVATED BLOOD LIPID LEVEL-RELATED DISEASES | KOREA RES INST OF BIOSCIENCE (KR) | 2004-04-21 | — | — | EP | disclosed |