Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117832 | 0.80 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14AURKA | |
| SCHEMBL8359225 | 0.73 | MAPT (0.44) | MAPK13MAPK12MAPK11MAPK14AURKA | |
| SCHEMBL31425489 | 0.72 | MAPT (0.56) | AURKAMEN1KMT2ANPC1LMNA | |
| SCHEMBL3270611 | 0.72 | MAPT (0.56) | AURKAMEN1KMT2ANPC1LMNA | |
| SCHEMBL205280 | 0.72 | GSK3B (0.80) | GSK3BPTPN1NPC1RAB9A | |
| SCHEMBL28121942 | 0.71 | GSK3B (0.59) | GSK3BPTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL19331717 | 0.70 | GSK3B (1.00) | GSK3BPTPN1MEN1KMT2ALMNA | |
| SCHEMBL7621 | 0.70 | GSK3B (1.00) | GSK3BPTPN1MEN1KMT2ALMNA | |
| SCHEMBL18849535 | 0.70 | GSK3B (1.00) | GSK3BPTPN1MEN1KMT2ALMNA | |
| SCHEMBL3066613 | 0.70 | KMT2A (0.66) | GSK3BPTPN1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087976-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-06-28 | — | — | WO | disclosed |