⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25197140 | 0.79 | — | — | |
| SCHEMBL4821020 | 0.77 | — | — | |
| SCHEMBL7603865 | 0.77 | LAP3 (0.32) | — | |
| SCHEMBL779544 | 0.77 | LAP3 (0.33) | — | |
| SCHEMBL11350927 | 0.73 | FOLH1 (0.43) | — | |
| SCHEMBL4812079 | 0.73 | FDPS (0.50) | — | |
| SCHEMBL3201591 | 0.71 | SMPD2 (0.31) | — | |
| SCHEMBL3805257 | 0.70 | FDPS (0.54) | — | |
| SCHEMBL7752112 | 0.70 | FOLH1 (0.50) | — | |
| SCHEMBL4644838 | 0.69 | BBOX1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443130-B1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NAT RECH SCIENT (FR) | 2016-08-03 | — | — | EP | disclosed |
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | UNIVERSITE D'ORLEANS (FR) | 2012-06-07 | — | — | US | disclosed |
| EP-2443130-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | Centre National de la Recherche Scientifique (FR) | 2012-04-25 | — | — | EP | disclosed |
| EP-2270021-A1 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | Centre National de la Recherche Scientifique (FR) | 2011-01-05 | — | — | EP | disclosed |
| WO-2010146127-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-12-23 | — | — | WO | disclosed |