Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 4/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118949 | 0.84 | SDCBP (0.42) | SMN1; SMN2TAOK1TAOK3LMNAKMT2A | |
| SCHEMBL12516657 | 0.81 | GAA (0.42) | SMN1; SMN2TAOK1TAOK3LMNAKMT2A | |
| SCHEMBL10119268 | 0.77 | CTSB (0.46) | SMN1; SMN2LMNAKMT2AGFERALDH1A1 | |
| SCHEMBL12516879 | 0.76 | CTSB (0.51) | TAOK1TAOK3LMNAKMT2AMEN1 | |
| SCHEMBL8968999 | 0.75 | HPGD (0.53) | SMN1; SMN2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8969003 | 0.75 | HPGD (0.53) | SMN1; SMN2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10118970 | 0.74 | PSMB5 (0.56) | CTSB | |
| SCHEMBL10118862 | 0.74 | PSMB5 (0.56) | CTSB | |
| SCHEMBL10119287 | 0.74 | CTSS (0.60) | CTSB | |
| SCHEMBL10118849 | 0.72 | HPGD (0.56) | SMN1; SMN2LMNAKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |