Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.46 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.46 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118994 | 0.94 | CTSB (0.51) | LMNACTSLCTSBCTSSCTSV | |
| SCHEMBL10118970 | 0.90 | PSMB5 (0.56) | CTSLCTSBCTSSCTRCPSMB5 | |
| SCHEMBL10118862 | 0.90 | PSMB5 (0.56) | CTSLCTSBCTSSCTRCPSMB5 | |
| SCHEMBL10118869 | 0.89 | PSMB5 (0.48) | CTSLCTSBCTSSCTSVPSMB5 | |
| SCHEMBL10118968 | 0.89 | CTSL (0.50) | CTSLCTSBCTSSCTSVPSMB5 | |
| SCHEMBL10118873 | 0.85 | PSMB5 (0.62) | CTSLPSMB5 | |
| SCHEMBL10118845 | 0.85 | CTSB (0.52) | CTSLCTSBCTSSPSMB5CTSK | |
| SCHEMBL10118811 | 0.85 | CTSB (0.57) | CTSLCTSBCTSSPSMB5CTSK | |
| SCHEMBL10118851 | 0.85 | CTSB (0.52) | CTSLCTSBCTSSPSMB5CTSK | |
| SCHEMBL10118859 | 0.83 | CTSL (0.51) | CTSLCTSBCTSSPSMB5CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |