Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 15/20 | 0.62 |
| ▸ | LONP1 | P36776 | 13/20 | 0.62 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.62 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.62 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.62 |
| ▸ | PSMB10 | P40306 | 10/20 | 0.62 |
| ▸ | PSMB11 | A5LHX3 | 9/20 | 0.62 |
| ▸ | PSMA7 | O14818 | 9/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 9/20 | 0.62 |
| ▸ | PSMA1 | P25786 | 9/20 | 0.62 |
| ▸ | PSMA2 | P25787 | 9/20 | 0.62 |
| ▸ | PSMA3 | P25788 | 9/20 | 0.62 |
| ▸ | PSMA4 | P25789 | 9/20 | 0.62 |
| ▸ | PSMA5 | P28066 | 9/20 | 0.62 |
| ▸ | PSMB4 | P28070 | 9/20 | 0.62 |
| ▸ | PSMB3 | P49720 | 9/20 | 0.62 |
| ▸ | PSMB2 | P49721 | 9/20 | 0.62 |
| ▸ | PSMA6 | P60900 | 9/20 | 0.62 |
| ▸ | PSMA8 | Q8TAA3 | 9/20 | 0.62 |
| ▸ | PSMB7 | Q99436 | 9/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118965 | 0.85 | LMNA (0.53) | PSMB5CTSL | |
| SCHEMBL10118968 | 0.84 | CTSL (0.50) | PSMB5CTSL | |
| SCHEMBL10118994 | 0.83 | CTSB (0.51) | PSMB5CTSL | |
| SCHEMBL10118970 | 0.82 | PSMB5 (0.56) | PSMB5CTSL | |
| SCHEMBL10118862 | 0.82 | PSMB5 (0.56) | PSMB5CTSL | |
| SCHEMBL12521476 | 0.82 | PSMB5 (0.72) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL10118869 | 0.82 | PSMB5 (0.48) | PSMB5CTSL | |
| SCHEMBL2127363 | 0.80 | LONP1 (0.76) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL20093516 | 0.80 | PSMB5 (0.75) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL11990768 | 0.80 | PSMB5 (0.75) | PSMB5LONP1PSMB8PSMB9PSMB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |