Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 10/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12518071 | 1.00 | LMNA (0.61) | LMNAPKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL20964503 | 0.82 | LMNA (0.51) | LMNAPKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12518275 | 0.81 | LMNA (0.65) | LMNA | |
| SCHEMBL8495772 | 0.79 | LMNA (0.61) | LMNAPKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL12518271 | 0.78 | ACE (0.50) | ACE | |
| SCHEMBL12518268 | 0.77 | POLB (0.48) | LMNAPKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8698541 | 0.76 | LMNA (0.58) | LMNAPKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9409874 | 0.74 | FNTA (0.60) | ACEFNTAFNTB | |
| SCHEMBL9409851 | 0.74 | FNTA (0.60) | ACEFNTAFNTB | |
| SCHEMBL9409861 | 0.74 | FNTA (0.60) | ACEFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |