Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119330 | 0.77 | ALDH1A1 (0.41) | HSD17B10ALDH1A1TSHREPHX2HTT | |
| SCHEMBL13506274 | 0.77 | MAPT (0.44) | HSD17B10ALDH1A1TSHREPHX2HTT | |
| SCHEMBL10119364 | 0.77 | ALDH1A1 (0.38) | HSD17B10ALDH1A1TSHREPHX2MAPT | |
| SCHEMBL6234511 | 0.76 | ALDH1A1 (0.41) | HSD17B10ALDH1A1TSHREPHX2P2RX7 | |
| SCHEMBL4086300 | 0.71 | EPHX1 (0.36) | ALDH1A1EPHX2KMT2A | |
| SCHEMBL1316622 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL13387469 | 0.70 | MEN1 (0.49) | ALDH1A1EPHX2MAPTKMT2A | |
| SCHEMBL24674956 | 0.70 | OPRM1 (0.41) | ALDH1A1TSHR | |
| SCHEMBL1605591 | 0.69 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TSHREPHX2P2RX7 | |
| SCHEMBL11296269 | 0.69 | THRB (0.41) | ALDH1A1TSHRHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | PCBP1, PUF60, PARG | HSD17B10 4481/4885ALDH1A1 3882/4885TSHR 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.