Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873261 | 0.91 | LMNA (0.43) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL10119355 | 0.91 | LMNA (0.42) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL872107 | 0.88 | KMT2A (0.42) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL845457 | 0.79 | HPGD (0.55) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL872441 | 0.77 | HPGD (0.38) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL845500 | 0.77 | HPGD (0.51) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL845495 | 0.77 | HPGD (0.51) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL845120 | 0.73 | HPGD (0.47) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL845476 | 0.73 | HPGD (0.46) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL873304 | 0.72 | PFKFB3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |