Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709628 | 0.95 | GHSR (0.42) | GHSRBMP1 | |
| SCHEMBL1709733 | 0.88 | GHSR (0.42) | GHSRBMP1 | |
| SCHEMBL1709705 | 0.85 | GHSR (0.41) | GHSRBMP1POLB | |
| SCHEMBL10122244 | 0.85 | GHSR (0.41) | GHSRBMP1POLB | |
| SCHEMBL1709655 | 0.83 | GHSR (0.60) | GHSRALDH1A1CYP2C19 | |
| SCHEMBL10122208 | 0.83 | GHSR (0.44) | GHSRBMP1 | |
| SCHEMBL10122207 | 0.82 | GHSR (0.49) | GHSRMEN1ALDH1A1KMT2A | |
| SCHEMBL10121851 | 0.80 | GHSR (0.56) | GHSRALDH1A1EPHX1 | |
| SCHEMBL10121689 | 0.78 | GHSR (0.61) | GHSRALDH1A1CYP2C19 | |
| SCHEMBL1709717 | 0.77 | GHSR (0.57) | GHSRKMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | ELIXIR PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088747-A1 | SULFONAMIDE CONTAINING COMPOUNDS AND USES THEREOF | GHSR, GHRHR, STS | GHSR 1/4885BMP1 2622/4885MEN1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.