SCHEMBL10122684

SCHEMBL10122684

c1ccc2cc(-c3c4ccccc4c(-c4cc(-c5c6ccccc6c(-c6ccc7ccccc7c6)c6ccccc56)cc(-c5cc6c7ccc8c9ccccc9oc8c7oc6c6c5oc5ccccc56)c4)c4ccccc34)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
CYP1A1 P04798 2/20 0.35
CYP1B1 Q16678 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 2/20 0.33
NPC1 O15118 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
AHR P35869 1/20 0.32
HPGD P15428 3/20 0.31
HSD17B10 Q99714 3/20 0.31
CYP3A4 P08684 2/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
CASP7 P55210 2/20 0.31
MEN1 O00255 1/20 0.31
ALPI P09923 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122679 0.95 GPR84 (0.36) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL10122686 0.95 GPR84 (0.36) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL16363431 0.92 GPR84 (0.34) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL10122326 0.91 GPR84 (0.40) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL10122603 0.90 GPR84 (0.38) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL10122300 0.90 ALOX5 (0.40) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL10122258 0.89 GPR84 (0.37) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL20416880 0.89 ALOX5 (0.42) ALOX5CYP1A1CYP1B1GPR84
SCHEMBL10122319 0.88 ALOX5 (0.40) ALOX5CYP1A1CYP1B1L3MBTL1TDP1
SCHEMBL10122327 0.88 GPR84 (0.36) ALOX5CYP1A1CYP1B1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 ALOX5 1779/4885CYP1A1 106/4885CYP1B1 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.