Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112675 | 0.84 | ALDH1A1 (0.42) | GAA | |
| SCHEMBL10112665 | 0.82 | KDM2B (0.43) | GAA | |
| SCHEMBL10112664 | 0.81 | GLA (0.39) | GAA | |
| SCHEMBL10112672 | 0.81 | GAA (0.38) | WDR91GAA | |
| SCHEMBL10112681 | 0.80 | GAA (0.38) | GAA | |
| SCHEMBL10112661 | 0.76 | SLC6A2 (0.44) | — | |
| SCHEMBL10112656 | 0.74 | GAA (0.41) | GAA | |
| SCHEMBL13959611 | 0.73 | AKT1 (0.38) | — | |
| SCHEMBL10112684 | 0.71 | CNR2 (0.42) | WDR91GAA | |
| SCHEMBL7291706 | 0.69 | ADRA1A (0.56) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135749-A2 | BIOMARKERS FOR PREDICTING SENSITIVITY TO CANCER TREATMENTS | GENENTECH, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012087336-A1 | AUTOPHAGY INDUCER AND INHIBITOR COMBINATION THERAPY FOR THE TREATMENT OF NEOPLASMS | GENENTECH, INC. (US) | 2012-06-28 | — | — | WO | disclosed |