⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562402 | 1.00 | — | — | |
| SCHEMBL928091 | 0.80 | — | — | |
| SCHEMBL1003091 | 0.80 | — | — | |
| SCHEMBL572491 | 0.76 | EP300 (0.42) | — | |
| SCHEMBL6586598 | 0.73 | CDK2 (0.40) | — | |
| SCHEMBL59477 | 0.72 | — | — | |
| SCHEMBL8166926 | 0.72 | ALDH1A1 (0.50) | — | |
| SCHEMBL190980 | 0.72 | — | — | |
| SCHEMBL5556 | 0.72 | — | — | |
| SCHEMBL31167436 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12398110-B2 | Second generation inhibitors of mitochondrial permeability transition pore with improved plasma stability | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| US-12071425-B2 | Phenoxy-pyridyl-pyrimidine compounds and methods of use | GENENTECH, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| CN-114026073-B | Quinazolin-4-one derivatives for the treatment of BRAF related diseases and disorders | ARRAY生物制药公司 | 2024-08-23 | — | — | CN | disclosed |
| EP-3849664-B1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2024-06-12 | — | — | EP | disclosed |
| US-11634409-B2 | Compounds for the treatment of BRAF-associated diseases and disorders | ARRAY BIOPHARMA INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-11634409-B2 | Compounds for the treatment of BRAF-associated diseases and disorders | ARRAY BIOPHARMA INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-02-23 | — | — | US | disclosed |
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-02-23 | — | — | US | disclosed |
| US-20220289721-A1 | COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS | ARRAY BIOPHARMA INC. (US) | 2022-09-15 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| WO-2004112736-A1 | METHOD AND COMPOSITIONS FOR COLORING HAIR WITH TAURATE COPOLYMERS | UNILEVER PLC (GB) | 2004-12-29 | — | — | WO | disclosed |
| CN-1551756-A | Composition for dyeing keratinous fibres comprising a particular dicationic diazo dye | �ź㴫 | 2004-12-01 | — | — | CN | disclosed |
| CN-1334718-A | Hair treatment method | NOVOZYMES AS (DK) | 2002-02-06 | — | — | CN | disclosed |
| EP-0349748-B1 | SUBSTITUTED N-ARYL-NITROGEN CONTAINING HETEROCYCLES | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |
| US-5118849-A | Arylamines intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-5039334-A | Herbicidal and plant growth-regulating substituted N-aryl nitrogen heterocycles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |
| US-5024694-A | Pre and postemergence herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-18 | — | — | US | disclosed |
| EP-0384192-A2 | N-Aryl nitrogen heterocycles having fluorine-containing substituents | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0349748-A1 | Substituted N-aryl-nitrogen containing heterocycles | BAYER AG (DE) | 1990-01-10 | — | — | EP | disclosed |