SCHEMBL572491

SCHEMBL572491

Nc1ccc(O)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.42
KAT2B Q92831 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
IDO1 P14902 2/20 0.42
HDAC3 O15379 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
CSNK2A2 P19784 1/20 0.41
CSNK2B P67870 1/20 0.41
CSNK2A1 P68400 1/20 0.41
CSNK2A3 Q8NEV1 1/20 0.41
ALOX15 P16050 5/20 0.40
HSD17B10 Q99714 4/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.38
ALDH1A1 P00352 5/20 0.37
HPGD P15428 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALOX12 P18054 2/20 0.37
MAPK1 P28482 1/20 0.37
GAA P10253 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5512090 0.82 EP300 (0.43) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL29987655 0.82 PIM1 (0.41) IDO1ALOX15HSD17B10CYP3A4ALDH1A1
SCHEMBL1512796 0.82 PIM1 (0.41) IDO1ALOX15HSD17B10CYP3A4ALDH1A1
SCHEMBL5513611 0.82 ALDH1A1 (0.45) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL25409311 0.81 EP300 (0.41) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL14908341 0.81 EP300 (0.41) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL573882 0.77 ALDH1A1 (0.43) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL30126048 0.77 EP300 (0.38) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL4847774 0.77 ALOX15 (0.43) EP300KAT2BKAT8IDO1HDAC3
SCHEMBL25006517 0.77 EP300 (0.38) EP300KAT2BKAT8IDO1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US claimed
CN-116178689-A Liquid crystal polymer and preparation method and application thereof 深圳大学 2023-05-30 CN claimed
US-7358397-B2 Preparation of halogenated 4-aminophenols LANXESS DEUTSCHLAND GMBH (DE) 2008-04-15 US claimed
US-20050143425-A1 Preparation of halogenated 4-aminophenols LANXESS DEUTSCHLAND GMBH (DE) 2005-06-30 US claimed
CN-1616412-A Process for the preparation of halogen containing 4-amino phenols BAYER CHEMICALS AG (DE) 2005-05-18 CN claimed
EP-1514865-A1 Process for the preparation of halogen containing 4-amino phenols Bayer Chemicals AG (DE) 2005-03-16 EP claimed
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
US-12479850-B2 Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2025-11-25 US disclosed
EP-3590516-B1 ANTITUMOR-EFFECT ENHANCER USING PYRAZOLO[3,4-D]PYRIMIDINE COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2025-09-03 EP disclosed
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US disclosed
WO-2025072673-A1 THIAZOLE DERIVATIVES AND THEIR USE AS IRE 1 INHIBITORS AL22.02.01, INC. (US) 2025-04-03 WO disclosed
US-12071425-B2 Phenoxy-pyridyl-pyrimidine compounds and methods of use GENENTECH, INC. (US) 2024-08-27 US disclosed
EP-3849664-B1 PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2024-06-12 EP disclosed
EP-1514865-A1 Process for the preparation of halogen containing 4-amino phenols Bayer Chemicals AG (DE) 2005-03-16 EP disclosed
US-20050038031-A1 Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders BAYER HEALTHCARE LLC 2005-02-17 US disclosed
WO-2004078748-A2 NOVEL BICYCLIC UREA DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS BAYER PHARMACEUTICALS CORPORATION (US) 2004-09-16 WO disclosed
EP-0818436-B1 Process for the preparation of 4-hydroxyanilines BAYER AG (DE) 2002-03-20 EP disclosed
US-6124504-A Process for preparing 4-hydroxyanilines BAYER AKTIENGESELLSCHAFT (DE) 2000-09-26 US disclosed
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed
EP-0818436-A1 Process for the preparation of 4-hydroxyanilines BAYER AG (DE) 1998-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038031-A1 Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders CCNC, UACA, SLC14A1 EP300 1523/4885KAT2B 1956/4885KAT8 2147/4885
US-12071425-B2 Phenoxy-pyridyl-pyrimidine compounds and methods of use XBP1, ERN1, ESR2 EP300 2994/4885KAT2B 4850/4885KAT8 4810/4885
US-20050143425-A1 Preparation of halogenated 4-aminophenols CYP4X1, HPD, CYP4F8 EP300 345/4885KAT2B 2322/4885KAT8 1208/4885
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture NOS1, NOS3, NOS2 EP300 4229/4885KAT2B 3650/4885KAT8 3693/4885
US-12479850-B2 Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof MET, MERTK, AXL EP300 3877/4885KAT2B 4514/4885KAT8 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.