Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TPMT | P51580 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815095 | 0.84 | CNR2 (0.54) | PTGS2HTTSLC6A2KDM4EALDH1A1 | |
| SCHEMBL6132065 | 0.77 | PTPN11 (0.58) | PTGS2TPMTCA12CA1CA2 | |
| SCHEMBL12402778 | 0.76 | MEN1 (0.54) | P2RY14HPGD | |
| SCHEMBL1010666 | 0.73 | ACMSD (0.46) | ABCC1HTTKDM4EALDH1A1HPGD | |
| SCHEMBL12193496 | 0.73 | KDM4E (0.65) | PTGS2TPMTHTTCA1CA2 | |
| SCHEMBL12193502 | 0.73 | KDM4E (0.65) | PTGS2TPMTHTTCA1CA2 | |
| SCHEMBL6959377 | 0.73 | PTGS2 (0.57) | PTGS2TPMTHTTCA12CA1 | |
| SCHEMBL2018471 | 0.72 | FABP3 (0.47) | HTTKDM4EALDH1A1HPGD | |
| SCHEMBL18288064 | 0.72 | ALOX15 (0.55) | PTGS2TPMTHTTCA12CA1 | |
| SCHEMBL505487 | 0.72 | CNR2 (0.67) | PTGS2TPMTHTTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1872173-B9 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL INC (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-1872173-B1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL INC (US) | 2010-04-14 | — | — | EP | disclosed |